Identification of MicroRNAs (miRNAs) small molecules ligands using biology-oriented synthesis

MicroRNAs (miRNAs) have recently emerged as an important class of small non-coding RNAs in regulating gene expression. Despite the very recent discovery of this class of small RNAs overwhelming evidence confirm a role in a variety of human diseases, such as viral infections, cancer and neurodegenerative diseases. The aim of this project is to extend our ongoing efforts on miRNAs  in CNS disorders and investigate miRNAs as drug targets.

The position requires a PhD level degree in the field of chemistry or biology (or both), with innovative scientific accomplishment demonstrated by a solid record of publications.

Applicants should prove a strong background in synthetic organic chemistry with expertise in library synthesis and hands on experience in a range of biochemical assays.

The applicant is required to have excellent verbal and written communication skills, competence in the English language and a strong motivation to contribute to improving the lives of patients through the creation of breakthrough medicines.

This position is based in Braine l’Alleud, Belgium. Positions are available for a period of 36 months with a starting date during 2012.

To apply for this position, please visit our Job Seekers' section and search for reference BRA00002588.

If you wish to be considered for this position, you are requested to submit a CV and covering letter detailing:

• Your motivation to undertake the chosen post-doctoral programme and passion for that specific area of science
• A detailed description of your scientific career to date
• Names of two referees
• Date from which you would be available