Identification of targets for the treatment of Parkinson's and Alzheimer's Disease

The project will focus on the identification of the role of the ubiquitin-proteasome system (UPS) pathway in the synaptic function and its implication in the pathology of Parkinson’s and Alzheimer’s diseases. The discovery of modulators of the UPS pathway may lead to new therapeutic principles for the treatment of neurodegenerative diseases. Using UCB experience and technological platform for target and drug discovery, the project will aim to identify new pharmacological approaches to the treatment of Parkinson’s and Alzheimer’s diseases.

The position requires a PhD level degree in the field of neurosciences, with innovative scientific accomplishment demonstrated by a solid record of publications.

The candidate is expected to have expertise/knowledge of:

• Neurobiology;
• Neuroanatomy;
• Cell signaling;
• Molecular biology and protein analysis;
• siRNA technology;
• High Content Imaging.

Expertise/knowledge of  Parkinson’s disease and Alzheimer’s disease would be an advantage.

The applicant is required to have excellent verbal and written communication skills, competence in the English language and a strong motivation to contribute to improving the lives of patients through the creation of breakthrough medicines.

This position is based in Braine l’Alleud, Belgium. Positions are available for a period of 36 months with a starting date during 2012.

To apply for this position, please visit our Job Seekers' section and search for reference BRA00002590.

If you wish to be considered for this position, you are requested to submit a CV and covering letter detailing:

• Your motivation to undertake the chosen post-doctoral programme and passion for that specific area of science
• A detailed description of your scientific career to date
• Names of two referees
• Date from which you would be available